Photochemical Amplification of Signal for Structure Elucidation (PASSE): Improved Homonuclear Correlation Spectroscopy
The determination of molecular structure is a key step in any synthetic chemistry project, drug discovery campaign, or natural product identification. Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and information rich analytical techniques available for the task, however, it is hampered by poor sensitivity.
A 3.5 year PhD studentship is available at Sussex to develop methods to improve the sensitivity of NMR experiments using photochemical methods. This project is particularly focused on improving the homonuclear methods used for modern structure elucidation.
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